Distinct Biomarker Profiles Distinguish Malawian Children with Malarial and Non-malarial Sepsis

Cytokine Profiles in Malawian Children Presenting with Uncomplicated Malaria, Severe Malarial Anemia, and Cerebral Malaria

Proinflammatory cytokines are involved in clearance of Plasmodium falciparum, and very high levels of these cytokines have been implicated in the pathogenesis of severe malaria. In order to determine how cytokines vary with disease severity and syndrome, we enrolled Malawian children presenting with cerebral malaria (CM), severe malarial anemia (SMA), and uncomplicated malaria (UCM) and healthy...

Malarial Fevers and Malarial Parasites

Malarial Fever with Aphasia

As malarial iever witn apna^ia is a condition spoken of in text*books, and but seldom seen in general practice, the notes of the following case may be of interest:? Jeer Bandhan, a Hindustani male, 20 years of age, was admitted into Hospital. Bassein, on 3rd March 1900, with a temperature of 102G, pulse 120, and respiration 38 per minute. He was unable to speak or give any account of himself. O...

Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia.

BACKGROUND The mechanisms of severe malarial anemia and cerebral malaria, which are extreme manifestations of Plasmodium falciparum malaria, are not fully understood. METHODS Children aged <6 years from southern Zambia presenting to the hospital with severe malarial anemia (n = 72), cerebral malaria (n = 28), or uncomplicated malaria (n = 66) were studied prospectively. Children with overlapp...

Malarial Fevers

the examination of the blood, the taking of specimens of blood, the staining and microscopic examination of the blood and the great necessity of being acquainted with thtf appearance of normal blood. The three species of parasite, other' blood parasites, the method of collecting sample of blood for serum diagnosis, the examination of sputum, etc. These subjects are rightly included in this book...